Piero Pizzi Cannella was born in 1955 in Rocca di Papa (Rome). He began painting when he was a child. In 1975, he began to attend the Accademia di Belle Arti of Rome and at the same time, he enrolled in the philosophy department at the University of “La Sapienza”. After his first conceptual  discoveries, he had his first solo exhibition in 1978 at the Galleria La Stanza in Roma. In 1982, he founded his studio in the former Pastificio Cerere (an old pasta factory) in the neighborhood of San Lorenzo. In the following years, he had numerous solo exhibitions: Rome (Galleria L’Attico), New York (Annina Nosei Gallery), Berlin (Folker Skulima Galerie), Basel (Galleria Triebold). Milan (Galleria Cannaviello), Paris (Vidal-Saint Phalle and Galleria Di Meo), Florence and Siena (Galleria Alessandro Bagnai), Bologna (Otto Gallery), Rome (Galleria Volume), Verona (Galleria Lo Scudo).
Museum and public spaces have also hosted his exhibits: “Diaries of War” at the Museo Civico di Gibellina, “Pizzi Cannella” at the seat of Santa Maria della Scala in Siena, “Carte 1980-2001” at the  Museo Archeologico of Aosta,  “Polittici” at the Castello Colonna Centro Internazionale di Arte Contemporanea of Genazzano, “Le Mappe del Mondo” at Teatro India in Rome, “Pizzi Cannella, Sept ou Huit Chambres” at the Hotel des Arts of Toulon, “Cattedrale” at the Macro in Rome. He has also participated in numerous collective exhibitions in Italy and abroad.
A number of his works are on permanent exhibtion in both private and public collections, including that of San Giorgio in Poggiale (Bologna), which hosts his series “Cattedrale”.